Depression Disorder Explained: Symptoms, Severity Levels, Types, and Effective Treatment Options

Coping strategies for managing depression disorder

Depression is one of the most common psychiatric pathologies found in the general population, along with anxiety disorders. The prevalence of depressive symptoms is estimated to be around 30%, with women being more frequently affected than men.

Depression Disorder: Signs and symptoms

The signs and symptoms of depressive disorder fall into four major categories:

1. Affective symptoms

Depressive mood characterized by persistent sadness lasting at least two weeks and which is unmotivated (which distinguishes it from the mourning reaction). 

It is also associated with a loss of pleasure or interest in activities that were previously considered pleasant, a lack of motivation, anxiety that can vary in intensity from mild to the appearance of panic attacks, irritability or irascibility. The symptoms include:

  • ✔️ Persistent sadness or low mood;
  • ✔️ Feelings of hopelessness or helplessness;
  • ✔️ Irritability or frustration, even over small matters;
  • ✔️ Loss of interest or pleasure in activities once enjoyed (anhedonia);
  • ✔️ Emotional numbness or detachment;
  • ✔️ Frequent tearfulness or crying spells;
  • ✔️ Feelings of guilt, worthlessness, or self-blame.


2. Cognitive symptoms

Characterized by concentration disorders, memory disorders, indecision, decreased self-esteem, pessimism about the future, unjustified ideas of guilt or devaluation, lack of hope and suicidal ideation (present in up to two thirds of those with depressive disorder). Cognitive symptoms include:

  • ✔️ Difficulty concentrating or making decisions;
  • ✔️ Indecisiveness or slowed thinking;
  • ✔️ Memory problems or forgetfulness;
  • ✔️ Negative or self-critical thoughts;
  • ✔️ Pessimistic outlook on the future;
  • ✔️ Difficulty thinking clearly or organizing thoughts;
  • ✔️ Rumination or dwelling on past failures.


3. Psychomotor symptoms

Either psychomotor slowness characterized by slow movements, reduced gestures and facial expressions, difficult communication, or on the contrary, psychomotor agitation. The symptoms include:

  • ✔️ Slowed movements or speech;
  • ✔️ Restlessness or agitation;
  • ✔️ Fidgeting or hand-wringing;
  • ✔️ Decreased physical activity;
  • ✔️ Impaired coordination or clumsiness;
  • ✔️ Sluggish facial expressions or reduced gestures;
  • ✔️ Difficulty initiating or completing tasks.


4. Somatic symptoms

Lack of emotional reactivity (i.e. inability to enjoy a pleasant event), marked fatigue, morning increase in depressive mood, decreased appetite or significant weight loss (more than 5% of body weight within a month), sleep disturbances or waking up two hours earlier than usual, decreased libido, multiple painful complaints or multiple somatic symptoms.

  • ✔️ Changes in appetite or significant weight loss/gain;
  • ✔️ Sleep disturbances (insomnia or hypersomnia);
  • ✔️ Fatigue or loss of energy;
  • ✔️ Aches and pains (headaches, back pain, muscle aches);
  • ✔️ Gastrointestinal issues (nausea, constipation, diarrhea);
  • ✔️ Changes in sexual desire or function;
  • ✔️ Psychosomatic complaints without clear medical cause.

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Depression disorder: Severity levels

There are several degrees of severity of depression, depending on the number of symptoms present and the degree of impairment of the individual’s functionality.

Mild depression

Mild depression is characterized by depressed mood or loss of interest or pleasure accompanied by a few additional symptoms (around 2-3 symptoms). The person experiences some difficulty in carrying out daily or professional activity, but this is usually not interrupted. The symptoms of mild depression include:

  • ✔️ Persistent low mood or sadness;
  • ✔️ Loss of interest or pleasure in daily activities;
  • ✔️ Mild fatigue or low energy;
  • ✔️ Slight changes in sleep or appetite;
  • ✔️ Occasional feelings of guilt or worthlessness;
  • ✔️ Minor difficulty concentrating;
  • ✔️ Symptoms present but daily functioning largely maintained.


Moderate depression

It is characterized by a greater number of additional symptoms and a considerable impairment of the person’s functionality. The person will most likely not be able to carry out their professional and daily activity.

  • ✔️ Noticeable low mood or sadness most of the day;
  • ✔️ Loss of interest or pleasure in most activities;
  • ✔️ Fatigue or low energy affecting daily tasks;
  • ✔️ Changes in sleep and appetite;
  • ✔️ Feelings of guilt, worthlessness, or hopelessness;
  • ✔️ Difficulty concentrating or making decisions;
  • ✔️ Daily functioning is impacted, but some tasks can still be managed.


Severe depression

Most of the symptoms specific to depression are present and the person is unable to carry out their activity. Suicidal ideation may also be present, along with other symptoms such as: delusions or even hallucinations. Requires hospitalization in most cases.

  • ✔️ Persistent and intense sadness or emptiness;
  • ✔️ Loss of interest or pleasure in almost all activities;
  • ✔️ Significant fatigue or loss of energy, making daily tasks very difficult;
  • ✔️ Major changes in sleep and appetite (insomnia, hypersomnia, weight loss or gain);
  • ✔️ Feelings of worthlessness, guilt, or hopelessness, often with self-blame;
  • ✔️ Severe difficulty concentrating or making decisions;
  • ✔️ Possible suicidal thoughts or behaviors;
  • ✔️ Daily functioning is severely impaired, requiring immediate professional intervention.


Subtypes of depressive disorder

Depending on the dominant symptomatology, the following subtypes are noted:

Atypical depression

The depressive mood is accompanied by hypersomnia (increased need for sleep), hyperphagia (increased appetite) and a feeling of heaviness, “like lead” in the upper and lower limbs.

Melancholic depression

At least four somatic symptoms are present, accompanied by a particular state of sadness, different from the sadness felt on the occasion of the death of a loved one. The person is also unable to feel joy on the occasion of pleasant events. The guilt felt can be significant.

Catatonic depression

A form of depression characterized by marked psychomotor inhibition. The person may stay in the same position for a long time, refuse to speak, eat, or communicate. Episodes of marked psychomotor agitation may also occur. There is a risk of malnutrition, the appearance of bedsores or pulmonary embolism due to motor inhibition.

Seasonal depression

Represents depression that appears periodically, correlated with a period of the year, mainly in autumn or winter and disappears in the other periods of the year.

Dysthymia

A less severe depressive state, but with a long duration (minimum 2 years).

Depression with postpartum onset

It is a depressive episode that begins within a maximum of 4 weeks of the birth of a child.

Depression with psychotic elements

It.is a severe depressive episode, in which delusional ideas appear (beliefs that the patient considers real, despite their implausibility or evidence to the contrary – for example: the belief that he is responsible for all the troubles in the world) or hallucinations (for example: he hears the voice of God condemning him for various mistakes).

Evolution and prognosis

Untreated, depressive disorder significantly interferes with the individual’s functionality, resulting in decreased professional efficiency, altered social and family relationships, withdrawal of the individual, neglect of personal hygiene and duties, intra-family or marital conflicts that can even lead to divorce, consumption of psychoactive substances. Suicidal ideation and suicide attempts are common in these individuals. 

Approximately 15% of people with depressive disorder die by suicide. Male gender, age over 45, feelings of guilt, self-blame, low self-esteem, a state of suffering and the need to find a solution to resolve emotional suffering are risk factors associated with suicide.

The evolution of depressive disorder under treatment is generally favorable, a significant percentage of patients achieve remission. Relapses throughout life are possible, however. The earlier the diagnosis and treatment are instituted, the more favorable the prognosis of patients with depressive disorder. Compliance with treatment is also very important, compliant patients have increased chances of complete remission of symptoms and a lower risk of relapse.

Depression Disorder Treatment

Therapeutic approaches vary depending on the severity of the disease, individual characteristics (age, sex, associated somatic diseases) and clinical symptomatology. Treatment involves pharmacological therapy and psychological interventions (cognitive-behavioral therapy being the most recommended).

Mild depression generally does not require drug treatment, psychotherapy being sufficient. If psychotherapy is ineffective or insufficient, then pharmacological therapy is resorted to. Moderate and severe forms require drug therapy.

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Antidepressants

There are several classes of antidepressants, the most used being those from the SSRI class (selective serotonin reuptake inhibitors). Representatives of the class are: escitalopram, sertraline, paroxetine, fluoxetine, etc. They are preparations that do not cause addiction and are well tolerated. Other antidepressants, belonging to other classes, can also be used, depending on the therapeutic response and clinical 

Symptomatology

Irtazapine, trazodone (trittico), venlafaxine (alventa), duloxetine, tianeptine (coaxil), etc.. 

Anxiolytics

It can be used as adjuvants for short periods of time, until the onset of the action of antidepressants. Benzodiazepines are most frequently used. Their use is NOT recommended for more than 6 weeks due to the risk of addiction.

Antipsychotics

The most commonly used include olanzapine and quetiapine. They are used in case of severe depressive episode, resistant to treatment or in case of psychotic symptoms.

❓ FAQs – Depression Disorder

What are the main symptoms of depression?

Depression includes sadness, loss of interest, fatigue, sleep changes, and difficulty concentrating.

Mild affects daily life slightly, moderate affects function more, and severe may cause suicidal thoughts.

See a psychiatrist if symptoms are persistent, severe, or affect daily life.

Depression can be treated with therapy, medications, or a combination depending on severity.

Yes, antidepressants are generally safe, well-tolerated, and non-addictive when used as prescribed.

Author details

Picture of Lincon Burrows

Lincon Burrows

As a psychiatry expert at Everts Health, I provide comprehensive Psychiatric Services focused on holistic healing. Specializing in Anxiety Treatment, Depression Disorder Treatment, and ADD & ADHD Treatment, I utilize advanced diagnostics like Brain View Neural Scan and TOVA Testing to refine evidence-based care plans. From DMDD Treatment to innovative Spravato Treatment, my goal is to offer elite Psychiatry care centered on your unique needs. I offer specialized support, including Individual Counseling and Therapy, Family Counseling and Therapy, Autism Evaluations Services, and Individual Group Therapy for All Mental Conditions. At Everts Health, your mental wellness is integrated with physical health. I collaborate daily with our Primary Care Doctor, Family Medicine Doctor, and Family Medicine Physician team. Whether you need a Psychiatrist In Texas or are seeking the Best Primary Care Doctor and Best Family Medicine Physician, I am here to guide your journey to lasting health.

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